Ad Soyad:
Cem Şimşek
Ünvanı:
Doç.Dr.
Bölüm:
Gastroenteroloji
İletişim:
Doç. Dr. Cem Şimşek, Hacettepe Üniversitesi Tıp Fakültesi Gastroenteroloji Bilim Dalı’nda öğretim üyesidir. 2013 yılında Hacettepe Üniversitesi Tıp Fakültesi’nden yüksek onur derecesiyle mezun olmuş, 2018 yılında Tıpta Uzmanlık Sınavı’nda (TUS) birincilikle Hacettepe Üniversitesi’nde İç Hastalıkları ihtisasına başlamıştır. 2021 yılında Gastroenteroloji yan dal uzmanlığını tamamlamış ve Hacettepe Üniversitesi Sağlık Bilimleri Enstitüsü’nde Temel Cerrahi Araştırmaları alanında doktora (Ph.D.) çalışmalarına devam etmektedir.
Dr. Şimşek, Harvard Tıp Fakültesi’ne bağlı Brigham and Women’s Hospital’da 16 ay süren ileri endoskopi ve bariyatrik endoskopi klinik fellowship programını tamamlamıştır. Bu süreçte, endoskopik submukozal diseksiyon (ESD) ve bariyatrik endoskopi alanlarında uzmanlaşmıştır. Ayrıca Johns Hopkins Üniversitesi’nde karaciğer nakli ve Barrett özofagusu üzerine araştırmalar yapmış, Avrupa Gastrointestinal Endoskopi Derneği (European Society of Gastrointestinal Endoscopy - ESGE) bursuyla Augsburg Üniversitesi’nde ileri endoskopi eğitimi almıştır. Cleveland Clinic Ohio ve Atina Mitera Hastanesi’nde misafir araştırmacı olarak görev yapmıştır. Dr. Şimşek’in araştırmaları gastrointestinal hastalıklar, obezite tedavisi ve karaciğer hastalıkları üzerine yoğunlaşmaktadır. Özellikle GastroGPT adlı yapay zeka dil modeliyle klinik görevlerde üstün performans gösteren çalışmalar yapmış, endoskopik kilo kaybettirici işlemler ve endoskopik tümör rezeksiyonu işlemleri üzerine yeni cihazların geliştirilmesine katkı sağlamıştır. Ulusal ve uluslararası alanda 100’den fazla bilimsel yayını ve 1000’den fazla atıfı bulunan Dr. Şimşek, çeşitli kongrelerde ödüller almış ve Avrupa Gastrointestinal Endoskopi Derneği (ESGE), Amerikan Gastrointestinal Endoskopi Derneği (American Society for Gastrointestinal Endoscopy - ASGE) ve Birleşik Avrupa Gastroenteroloji Derneği (United European Gastroenterology - UEG) gibi prestijli derneklerin komitelerinde aktif olarak görev yapmaktadır. Dr. Şimşek’in ilgi alanları arasında ileri endoskopi (ERCP, EUS, POEM), reflü hastalığı ve tedavisi, obezite, endoskopik kilo kaybettirici işlemler (tüp mide, mide balonu), erken evre tümörlerin endoskopik tedavisi (ESD) ve karaciğer hastalıkları yer almaktadır.Peer-reviewed Publications: Original Research
1. Bujanda L et al.; Hp-EuReg investigators. Effectiveness of Helicobacter pylori Treatments According to Antibiotic Resistance. Am J Gastroenterol. 2024 Jan 22. doi: 10.14309/ajg.0000000000002600. Epub ahead of print. PMID: 37983769.
2. C. Simsek, E. de-Madaria, A. Ebigbo, P. Vanek, O. Elshaarawy, A. M. Voiosu, G. Antonelli, R. Turro, J. Gisbert, O. P. Nyssen, C. Hassan, H. Messmann, R. Jalan H. Demir, B. Tinaz, H. M. Erol. GastroGPT: First Specialty-Specific AI Language Model Outperforms General Models Across Key Clinical Tasks. UEG Journal (2023). Abstract: United European Gastroenterol J, 11: 919-940. {Original article accepted in the same Journal}
3. Durak MB, Simsek C, Yüksel I. Clinical Outcomes of Older Patients with Non-Variceal Upper Gastrointestinal Bleeding Taking Anti-Thrombotic or Non-Steroidal Anti-Inflammatory Agents. Turk J Gastroenterol. 2023 Sep;34(9):918-924. doi:10.5152/tjg.2023.23226. PMID: 37603303.
4. Durak, M. B., Simsek, C., Cagir, Y., & Yuksel, I. (2023). AIMS65 Outperforms Other Scoring Systems for Non-Variceal Upper Gastrointestinal Bleeding in Octogenarians: A Prospective Study. International Internal Medicine Journal, 1(4), 155-163.
5. Durak M. B. , Simsek C. , Kılıç Z. M. Y. Endoscopic Treatment of Postoperative Esophageal Anastomotic Strictures: A Single Center Experience. J Contemp Med. 2023; 13(4): 603-608.
6. Akcay K, Ayhan H, Sezer Ceren RE, Simsek C, Abbasoglu O. Comparison of normal saline and antiseptic solution effect on the early peristomal infection rates of patients with percutaneous endoscopic gastrostomy tubes: A randomized double- blind study. Nutr Clin Pract. 2023 Jul 20. doi: 10.1002/ncp.11041. Epub ahead of print. PMID: 37475525.
7. Durak MB, Simsek C, Inan B, Yuksel I. Ileocecal valve that cannot be intubated in Crohn's disease: is this a sign of poor prognosis? Int J Colorectal Dis. 2023 Apr 19;38(1):103. doi: 10.1007/s00384-023-04401-0. PMID: 37072530.
8. Karaoglu DA, Uner M, Simsek C, Gure AO, Demirkol-Canli S. Transcriptomic Analysis of Hepatitis B Infected Liver for Prediction of Hepatocellular Carcinoma. Biology (Basel). 2023 Jan 26;12(2):188. doi: 10.3390/biology12020188. PMID: 36829466; PMCID: PMC9952979.
9. Baghdadi A, Luu HT, Shaghaghi M, Ghadimi M, Simsek C, Xu Z, Hazhirkarzar B, Motaghi M, Hammami M, Clark JM, Gurakar A, Kamel IR, Kim AK. Magnetic Resonance Imaging Predictors of Hepatocellular Carcinoma Progression and Dropout in Patients in Liver Transplantation Waiting List. Transplant Direct. 2022 Oct 18;8(11):e1365. doi: 10.1097/TXD.0000000000001365. PMID: 36284930; PMCID: PMC9584197.
10. Yang D, Aihara H, Hasan MK, Simsek C, Khan H, Brar TS, Gorrepati VS, Forde JJ, Kadkhodayan K, Arain MA, Draganov PV. Novel single-operator through-the-scope traction device for endoscopic submucosal dissection: Outcomes of a multicenter randomized pilot ex-vivo study in trainees with limited endoscopic submucosal dissection experience (with video). DEN Open. 2022 Oct 10;3(1):e174. doi: 10.1002/deo2.174. PMID: 36247316; PMCID: PMC9549878.
11. Guzelbulut F, Karaogullarindan U, Akkiz H, Altintas E, Demirtas CO, BahadirO, Keklikkiran C, Yildirim AE, Gumussoy M, Balci HR, Gokcen P, Gokce DT, Simsek C, Turan I, Can G, Gokbulut V, Yaras S, Adali G, Akdogan RA, Avcioglu U, DemirM, Doganay HL, Vatansever S, Sumer H, Dilber F, Kayhan MA, Balaban HY, Simsek H,Ozdogan OC, Akarca US, Karasu Z, Gunsar F, Idilman R. Characteristics ofpatients with hepatocellular carcinoma: A multicenter study. Hepatol Forum. 2022Sep 23;3(3):71-76. doi: 10.14744/hf.2022.2022.0028. PMID: 36177097; PMCID: PMC9510736.
12. Thompson CC, Jirapinyo P, Shah R, Simsek C. Gastroplasty with Endoscopic Myotomy (GEM) for the Treatment of Obesity: Preliminary Efficacy and Physiologic Results. Gastroenterology. 2022
Nov;163(5):1173-1175. doi: 10.1053/j.gastro.2022.07.077. Epub 2022 Aug 10. PMID: 35961376.
13. Balaban HY, Aslan AT, Akdoğan-Kittana FN, Alp A, Dağ O, Ayar ŞN, Vahabov C Simsek C, Yıldırım T, Göker H, Ergünay K, Erdem Y, Büyükaşık Y, Şimşek H Hepatitis E Virus Prevalence and Associated Risk Factors in High-Risk Groups: ACross-Sectional Study. Turk J Gastroenterol. 2022 Jul;33(7):615-624. doi:10.5152/tjg.2022.21493. PMID: 35879919
14. Simsek C, Guven Deniz C, Sahin T, Ceylan F, Dizdar O, Yalcin S. Pilot Study: Machine Learning Models Predict Early Post-Operative Relapse in Pancreatic Cancer. Journal of oncological sciences, 2021, 7.3: 115-124. DOI:10.37047/jos.2021-84326
15. Ma K, Kalra A, Tsai HL, Okello S, Cheng Y, Meltzer SJ; Esophageal Squamous Cell Carcinoma Consortium. Accurate Nonendoscopic Detection of Esophageal Squamous Cell Carcinoma Using Methylated DNA Biomarkers. Gastroenterology. 2022 Aug;163(2):507-509.e2. doi:10.1053/j.gastro.2022.04.021. Epub 2022 Apr 26. PMID: 35483446.
16. Simsek C, Guven DC, Sahan O, Sahin T, Tekin IE, Balaban YH, Yalcin S Artificial intelligence method to predict overall survival of hepatocellular carcinoma. Hepatology Forum 2021 May 2;2:64-68 DOI: 10.14744/hf.2021.2021.0017
17. Nyssen OP, Vaira D, Pérez Aísa Á, Rodrigo L, Castro-Fernandez M, Jonaitis L,Tepes B, Vologzhanina L, Caldas M, Lanas A, Lucendo AJ, Bujanda L, Ortuño J,Barrio J, Huguet JM, Voynovan I, Lasala JP, Sarsenbaeva AS, Fernandez-Salazar L,Molina-Infante J, Jurecic NB, Areia M, Gasbarrini A, Kupčinskas J, Bordin D,Marcos-Pinto R, Lerang F, Leja M, Buzas GM, Niv Y, Rokkas T, Phull P, Smith S,Shvets O, Venerito M, Milivojevic V, Simsek I, Lamy V, Bytzer P, Boyanova L,Kunovský L, Beglinger C, Doulberis M, Marlicz W, Goldis A, Tonkić A, Capelle L,Puig I, Megraud F, Morain CO, Gisbert JP; European Registry on Helicobacterpylori Management Hp-EuReg Investigators. Empirical Second-Line Therapy in 5000Patients of the European Registry on Helicobacter pylori Management (Hp-EuReg).Clin Gastroenterol Hepatol. 2021 Dec 23:S1542-3565(21)01349-5. doi:10.1016/j.cgh.2021.12.025. Epub ahead of print. PMID: 34954341.
18. Simsek C, Armagan B, Sari A, Erden AS, Kilic L, Akdogan A. Fecal S100A12 in Takayasu Arteritis Predicts Disease Activity and Intestinal Involvement. Rheumatol Int. 2021 Sep 12. doi: 10.1007/s00296- 021-04981-6. PMID: 34514516.
19. Bujanda L, Nyssen OP, Vaira D, Saracino IM, Fiorini G, Lerang F, GeorgopoulosS, Tepes B, Heluwaert F, Gasbarrini A, Rokkas T, Bordin D, Smith S, Lamy V,Caldas M, Resina E, Muñoz R, Cosme Á, Puig I, Megraud F, O'Morain C, Gisbert JP; The Hp-EuReg Investigators. Antibiotic Resistance Prevalence and Trends in Patients Infected with Helicobacter pylori in the Period 2013-2020: Results of the European Registry on H. pylori Management (Hp-EuReg). Antibiotics (Basel). 2021 Sep 1;10(9):1058. doi: 10.3390/antibiotics10091058.PMID: 34572640; PMCID: PMC8471667.
20. Caldas M, Pérez-Aisa Á, Tepes B, Keco-Huerga A, Bujanda L, Lucendo AJ, Rodrigo L, Vaira D, Fernández-Salazar L, Huguet JM, Pérez-Lasala J, Jurecic NB, Fadeenko G, Barrio J, Areia M, Ortuño J, Pellicano R, Leja M, Molina-Infante J, Bogomolov P, Alekseenko S, Domínguez-Cajal M, Gómez-Camarero J, Ntouli V, Martínez-Domínguez SJ, Ruiz-Zorrilla R, Núñez O, Sarsenbaeva AS, Almela P, Phull P, Espada M, Puig I, Nyssen OP, Mégraud F, O'Morain C, Gisbert JP; the
Hp-EuReg Investigators. The Role of Statins on Helicobacter pylori Eradication: Results from the European Registry on the Management of H. pylori (Hp- EuReg). Antibiotics (Basel). 2021 Aug 11;10(8):965. doi: 10.3390/antibiotics10080965. PMID: 34439015; PMCID: PMC8388917.
21. Simsek C, Sahin T, Sahin H, Tekin IE, Balaban YH, Sivri B. Artificial intelligence to predict overall survivals of patients with cirrhosis and outcomes of variceal bleeding. Hepatology Forum 2021 May 2;2:55-59 DOI: 10.14744/hf.2021.2021.0016
22. Simsek, C., Armağan, B., Hymabaccus, B., Alper, Sari., Erden, A., Kiliç, L. And Akdoğan, A., 2021. Fecal S100A12 as a Biomarker in Behcet’s Disease. Acibadem University Health Sciences Journal 12(3), pp.616-624 DOI: 10.31067/acusaglik.928333
23. Simsek C, Tekin E, Sahin H, Sahin TK, Balaban YH, Artificial Intelligence to Predict Esophageal Varices in Patients with Cirrhosis. Acibadem University Health Sciences Journal 12(3), pp.625-629. DOI: 10.31067/acusaglik.928498
24. Song JH, Tieu AH, Cheng Y, Ma K, Akshintala VS, Simsek C, Prasath V, Shin EJ, Ngamruengphong S, Khashab MA, Abraham JM, Meltzer SJ. Novel Long Noncoding RNA miR205HG Functions as an Esophageal Tumor-Suppressive Hedgehog Inhibitor. Cancers (Basel). 2021 Apr 3;13(7):1707. doi: 10.3390/cancers13071707. PMID: 33916875; PMCID: PMC8038513.
25. Ayhan H, Akcay K, Olmez YN, Simsek C, Abbasoglu O. Redetermining the Cut-Off Point of Peristomal Infection Scoring: Methodological Research. JPEN J Parenter Enteral Nutr. 2022 Feb;46(2):462-468. doi: 10.1002/jpen.2122. Epub 2021 Jun 3. PMID: 33904189.
26. Simsek C, Uner M, Ozkara F, Akman O, Akyol A, Kav T, Sokmensuer C, Gedikoglu G. Comprehensive clinicopathologic characteristics of intraabdominal neurogenic tumors: Single institution experience. World J Clin Cases. 2021 Apr 6;9(10):2218-2227. doi: 10.12998/wjcc.v9.i10.2218. PMID: 33869597; PMC8026837.
27. Nyssen OP, Perez-Aisa A, Tepes B, Castro-Fernandez M, Kupcinskas J, Jonaitin Hp-EuReg Investigators. Adverse Event Profile During the Treatment of Helicobacter pylori: A Real-World Experience of 22,000 Patients from the European Registry on H. pylori Management (Hp-EuReg). Am J Gastroenterol. 2021 Jun 1;116(6):1220-1229. doi: 10.14309/ajg.0000000000001246. PMID: 33840725.
28. Strauss AT, Ishaque T, Weeks S, Hamilton JP, Simsek C, Durand CM, Massie AB, Segev DL, Gurakar A, Garonzik-Wang JM. Pretransplant Hepatitis C Virus Treatment Decreases Access to High- quality Livers. Transplant Direct. 2021 Mar 22;7(4):e684. doi: 10.1097/TXD.0000000000001127.
PMID: 34549082; PMCID: PMC8440014.
29. Simsek C, Lacin S, Ece E, Yalcin S V600E and Non-V600E BRAF Mutations in Colorectal Cancer: Clinicopathologic Correlations in a Single Institution International Journal of Hematology and Oncology. 2021 Jan 1;31(4):043-9. doi: 10.4999/uhod.214010
30. Parlak E, Simsek C, Koksal AS, Eminler AT, Unal E, Ciftci TT, Akinci D, Yilmaz S. The Classification of Biliary Strictures in Patients with Right Lobe Liver Transplant Recipients and Its Relation to Traversing the Stricture with a Guidewire. Transplantation. 2022 Feb 1;106(2):328-336. doi: 10.1097/TP.0000000000003738. PMID: 33724243.
31. Balaban HY, Aslan AT, Ayar ŞN, Dağ O, Alp A, Simsek C, Vahabov C, Yildirim T, Göker H, BüyükaŞik Y, Şimşek H. Lack of Awareness of Hepatitis B Screening and Vaccination in High-Risk Groups. urk J Med Sci. 2021 Jun 28;51(3):1229-1233. doi: 10.3906/sag-2008-18. PMID: 33433973; PMCID: PMC8283497.
32. Farha J, Gebran S, Itani MI, Simsek C, Abbarh S, Lopez A, Haq Z, Koller K, Dunlap M, Adam A, Khashab MA, Oberbach A, Schweitzer M, Badurdeen D, Kumbhari V. Transoral Outlet Reduction (TORe): Could Additional Sutures Cause More Harm? Endoscopy. 2021 Oct;53(10):1059-1064. doi: 10.1055/a-1325-4324. Epub 2021 Feb 8. PMID: 33254242.
33. Nyssen OP, Bordin D, Tepes B, Pérez-Aisa Á, Vaira D, Caldas M, Bujanda L ; Hp-EuReg Investigators. European Registry on Helicobacter pylori management (Hp-EuReg): patterns and trends in first- line empirical eradication prescription and outcomes of 5 years and 21 533 patients. Gut. 2021 Jan;70(1):40-54. doi: 10.1136/gutjnl-2020-321372. Epub 2020 Sep 21. PMID: 32958544.
34. Efe C, Simsek C, Batıbay E, Calışkan AR, Wahlin S. Feasibility of telehealth in the management of autoimmune hepatitis before and during the COVID-19 pandemic. Expert Rev Gastroenterol Hepatol. 2020 Dec;14(12):1215-1219. doi: 10.1080/17474124.2020.1822734. Epub 2020 Sep 17. PMID: 32909852.
35. Farha, J., Mcgowan, C., Hedjoudje, A., Itani, M., Abbarh, S., Simsek, C., Ichkhanian, Y., Vulpis, T., James, T., Fayad, L., Khashab, M., Oberbach, A., Badurdeen, D., & Kumbhari, V. (2020). Endoscopic Sleeve Gastroplasty: Suturing the Gastric Fundus Does Not Confer Benefit. Endoscopy. 2021 Jul;53(7):727-731. doi: 10.1055/a-1236-9347. Epub 2020 Aug 8. PMID: 32777827.
36. Simsek C; Kim A; Ma M; Danis N; Gurakar M; Cameron AM; Philosophe B; Garonzik-Wang J; Ottmann S; Gurakar A; Saberi B. Recurrence of Hepatocellular Carcinoma Following Deceased Donor Liver Transplantation: Case Series Hepatoma Res. 2020;6:11. doi: 10.20517/2394-5079.2019.51. Epub 2020 Mar 20. PMID: 32582866; PMCID: PMC7313412.
37. Runge T, Yang J, Fayad L, Itanı MI, Dunlap M, Koller K, Mullin GE, Simsek C, Badurdeen D, Kalloo AN, Khashab MA, Kumbhari V. Anatomical Configuration of the Stomach Post-Endoscopic Sleeve
Gastroplasty (ESG) - What are the Sutures Doing. Obes Surg. 2020 May;30(5):2056-2060. doi: 10.1007/s11695-019-04311-7. Erratum in: Obes Surg. 2020 Mar 10;: PMID: 31858398.
38. Fayad L, Trindade AJ, Benias PC, Simsek C, Raad M, Badurdeen D, Hill C, Brewer Gutierrez, O, Fayad G, Dunlap M, Kalloo AN, Khashab MA, Thompson CC, Canto C; Kumbhari V. Cryoballoon Ablation for Gastric Pouch And/or Outlet Reduction in Patients with Weight Regain Post Roux-En-Y Gastric Bypass. Endoscopy 2020 Mar;52(3):227-230. doi: 10.1055/a-1086-3433. Epub 2020 Jan 23.
39. Fayad L, Simsek C, Oleas R, Ichkhanian Y, Fayad GE, Ngamreungphong S, Schweitzer M, Oberbach A, Kalloo AN, Khashab MA, Kumbhari V. Safety and Efficacy of Endoscopically Secured Fully Covered Self-Expandable Metallic Stents (FCSEMS) for Post-Bariatric Complex Stenosis. Obes Surg. 2019 Nov;29(11):3484-3492. doi: 10.1007/s11695-019-04021-0. PMID: 31254212.
40. Barrichello S, Badurdeen D, Hedjoudje A, Neto MG, Yance R, Veinert A, Fayad L, Simsek C, Grecco E, de Souza TF, Teixeira C, Nunes GC, Kalloo AN, Khashab MA, Kumbhari V. The Effect of the Intra-gastric Balloon on Gastric Emptying and the DeMeester Score. Obes Surg. 2020 Jan;30(1):38-45. doi: 10.1007/s11695-019-04039-4. PMID: 31254210.
41. Simsek C, Ichkhanian Y, Fayad L, Steele KE, Schweitzer MA, Lamond K, Vosoughi K, Doshi J, Shah T, Oberbach A, Al-Sabban A, Gandsas A, Kalloo AN, Khashab MA, Kumbhari V. Secured Lumen-Apposing Fully Covered Metallic Stents for Stenoses in Post-Bariatric Surgery Patients. Obes Surg. 2019 Aug;29(8):2695-2699. doi: 10.1007/s11695-019-03906-4. PMID: 31055739.
42. Fayad L, Schweitzer M, Raad M, Simsek C, Oleas R, Dunlap MK, Shah T, Doshi J, El Asmar M, Oberbach A, Singh VK, Steele K, Magnussen T, Kalloo AN, Khashab MA, Kumbhari V. A Real- World, Insurance-Based Algorithm Using the Two-Fold Running Suture Technique for Transoral Outlet Reduction for Weight Regain and Dumping Syndrome After Roux-En-Y Gastric Bypass Obes Surg. 2019 Jul;29(7):2225-2232. doi: 10.1007/s11695-019-03828-1. PMID: 30937874.
43. Fayad L, Simsek C, Cheskin A, Adam B, Badurdeen C, Hill C, Agnihotri A, Dunlap M, Khashab M, Kalloo A, Kumbhari V, Endoscopic Sleeve Gastroplasty and Intragastric Balloon: Efficacy, Durability and Safety Interpretation of data for the work. Endoscopy. 2019 Jun;51(6):532-539. doi: 10.1055/a-0852-3441. Epub 2019 Mar 6. PMID: 30841009.
44. Wang Z, Kambhampati S, Cheng Y, Ma K, Simsek C, Tieu AH, Abraham JM, Liu X, Prasath V, Duncan MD, Stark A, Trick A, Tsai HL, Wang H, He Y, Khashab MA, Ngamruengphong S, Shin EJ, Wang TH, Meltzer SJ. Methylation Biomarker Panel Performance in EsophaCap Cytology Samples for Diagnosing Barrett's Esophagus: A Prospective Validation Study. Clin Cancer Res. 2019 Apr 1;25(7):2127- 2135. doi: 10.1158/1078-0432.CCR-18-3696. Epub 2019 Jan 22. PMID: 30670490; PMCID: PMC6594757.
45. Simsek C, Selek S, Koca M, Haznedaroglu IC. Proteomic and transcriptomic analyses to explain the pleiotropic effects of Ankaferd blood stopper. SAGE Open Med. 2017 Jul 27;5:2050312117722569. doi:
10.1177/2050312117722569. eCollection 2017. Review. PubMed PMID: 28839937; PubMed Central PMCID: PMC5536373.
Peer-reviewed Publications: Invited Reviews, Brief Reports, Correspondences
1. Simsek C, Wahlen S, Efe C. Autoimmune Hepatitis, Mycophenolate mofetil versus Azathipurine Accepted as First Line Therapy. Journal of Hepatology {Accepted to Publication, JHEPAT-D-24-00394}
2. Simsek C, Dugic A, Domislovic V, Te Groen M, Hadefi A, Kravchuk S, Porcari S,Sochnieva A, Sousa P, Acedo P; UEG Friends of Young Talent Group. Young GI Angle: The young perspective of the UEG White Book 2 by the Friends of the UEG Young Talent Group. United European Gastroenterol J. 2023 Oct 25. doi: 10.1002/ueg2.12478. Epub ahead of print. PMID: 37880151.
3. Samaha C, Chaaban H, Simsek C, Danis N, Lin JS, Gurakar A. Practice patterns and considerations in liver transplantation from living donors with high BMI: A review. Hepatol Forum. 2023 Sep 20;4(3):145- 149. doi: 10.14744/hf.2023.2023.0030. PMID: 37822307; PMCID: PMC10564250.
4. Staudacher JJ, Burisch J, Sousa P, Salaga M, Pellino G, Sidiropoulos O, Groen MT, Mandorfer M, Schwabl P, Straume Z, Bîrlog C, Dugic A, Simsek C, Jovanovic J, Kani HT, Qejvani O, Fennessy AM, Gorcheva Z, Kral J, Zanetto A, Duricek M, Domislovic V, Acedo P, Schlosser S; friends of the Young Talent Group. Young gastroenterologists angle: Friends of the UEG young talent group consensus statement on the structure of young gastroenterology sections. United European Gastroenterol J. 2023 Jul;11(6):578-581. doi: 10.1002/ueg2.12430. Epub 2023 Jun 25. PMID: 37357495; PMCID: PMC10337734.
5. Esposito I, Simsek C, Nowak A, Tiniakos D; UEG Equality & Diversity Group United European Gastroenterology Equality and Diversity Plan. United European Gastroenterol J. 2023 Jun;11(5):484- 487. doi: 10.1002/ueg2.12415. Epub 2023 May 20. PMID: 37209358; PMCID: PMC10256985.
6. Thompson CC, Jirapinyo P, Shah R, Simsek C. Gastroplasty with endoscopic myotomy for the treatment of obesity. VideoGIE. 2023 Apr 2;8(5):193-195. doi: 10.1016/j.vgie.2022.12.004. PMID: 37197162; PMCID: PMC10183641.
7. Simsek C, Kaan HL, Aihara H. Future Directions for Robotic Endoscopy–Artificial Intelligence (Ai), Three- Dimensional (3d) Imaging And Natural Orifice Transluminal Endoscopic Surgery. Techniques and Innovations in Gastrointestinal Endoscopy, 2022 ISSN 2590-0307 doi:10.1016/j.tige.2022.10.001.
8. Simsek C, Aihara H. Training in Endoscopic Submucosal Dissection in the United States: The Current Paradigm. Gastrointest Endosc Clin N Am. 2023 Jan;33(1):41-53. doi: 10.1016/j.giec.2022.07.003.
PMID: 36375885.
9. Simsek C, Thompson CC, Alkhateeb KJ, Jofre SA, Aihara H. Novel articulating through-the-scope traction device. VideoGIE. 2022 Aug 20;7(10):353-357. doi:10.1016/j.vgie.2022.07.002. PMID: 36238810; PMCID: PMC9552815.
10. Simsek C, Ryou, M., Thompson, C. C., & Aihara, H. (2022). Endoscopic submucosal dissection with ductotomy for the resection of a gastric duplication cyst with a communicating duct. VideoGIE. 2022 May 26;7(8):280-283. doi: 10.1016/j.vgie.2022.04.003. PMID: 36034066; PMCID: PMC9414580.
11. Simsek C, Lee Linda S. Machine learning in endoscopic ultrasonography and the pancreas: The new frontier?. Artificial Intelligence in Gastroenterology, 2022, 3.2: 54-65. doi: 10.35712/aig.v3.i2.54
12. Sahin T, Simsek C, Balaban HY. Practical points that gastrointestinal fellows should know in management of COVID-19. World J Clin Cases. 2022 Jun 6;10(16):5133-5145. doi: 10.12998/wjcc.v10.i16.5133. PMID: 35812670; PMCID: PMC9210885.
13. Muhammad, H., Zaffar, D., Tehreem, A., Ting, P. S., Simsek, C., Gokcan, H., ... & Idilman, R. (2021). HBV/HDV management after liver transplantation. Journal of Liver Transplantation, 4, 100046. doi: 10.1016/j.liver.2021.100046
14. Acedo P, Simsek C, Heinrich H. Young GI angle: What being a myUEG young GI associate can offer you- Check it out! United European Gastroenterol J. 2022 Feb;10(1):134-135. doi: 10.1002/ueg2.12199. Epub 2022 Feb 7. PMID: 35129306; PMCID: PMC8830286.
15. Muhammad H, Zaffar D, Tehreem A, Ting PS, Simsek C, Turan I, Alqahtani S, Saberi B, Gurakar
A. An Update on Usage of High-Risk Donors in Liver Transplantation. J Clin Med. 2021 Dec 31;11(1):215. doi: 10.3390/jcm11010215. PMID: 35011956; PMCID: PMC8746244.
16. Muhammad H, Tehreem A, Ting PS, Gurakar M, Li SY, Simsek C, Alqahtani SA, Kim AK, Kohli R, Gurakar A. Hepatocellular Carcinoma and the Role of Liver Transplantation: A Review. J Clin Transl Hepatol. 2021 Oct 28;9(5):738-748. doi: 10.14218/JCTH.2021.00125. Epub 2021 Jun 7. PMID: 34722189; PMCID: PMC8516838.
17. Simsek C, Erul E, Balaban YH. The Role of Gastrointestinal System on Transmission and Pathogenesis of SARS-COV-2. World J Clin Cases. 2021 Jul 16;9(20):5427-5434. doi: 10.12998/wjcc.v9.i20.5427. PMID: 34307596; PMCID: PMC8281423.
18. Metin O, Simsek C, Gürakar A. Update on liver transplantation-newer aspects. Turk J Med Sci. 2020 Nov 3;50(SI-2):1642-1650. doi: 10.3906/sag-2002-17. PMID: 32222125.
19. Guven DC, Aktas BY, Simsek C, Aksoy S. Gut microbiota and cancer immunotherapy: prognostic and therapeutic implications. Future Oncol. 2020 Mar;16(9):497-506. doi: 10.2217/fon-2019-0783. Epub
2020 Feb 26. PMID: 32100550.
20. Aljabban, J., Danis, N., Gurakar, M., Khorfan, K., Aljabban, N., Simsek, C., Hussam Salhi, Maryam Panahiazar, Dexter Hadley, Ahmet Gurakar Saberi, B. (2020). Hepatol Forum. 2020 Jan 17;1(1):1-7. doi: 10.14744/hf.2019.0002. PMID: 35949665; PMCID: PMC9344372.
21. Simsek C. Considering the first randomized trial of peroral endoscopic myotomy versus surgical myotomy for achalasia. Turk J Gastroenterol. 2020 Feb;31(2):190-192. doi: 10.5152/tjg.2020.250220. PMID: 32141831; PMCID: PMC7062137.
22. Simsek C. Covering the Cover. Turk J Gastroenterol. 2019 Oct;30(10):863-864. doi: 10.5152/tjg.2019.250919. PubMed PMID: 31625930; PubMed Central PMCID:PMC6812957.
23. Tasdogan BE, Akosman S, Gurakar M, Simsek C, Gurakar A. Update on Immunosupression in Liver Transplantation. Euroasian J Hepatogastroenterol. 2019 Jan-Jun;9(1):34-39. doi: 10.5005/jp- journals-10018-129
24. Çiftçibaşı Örmeci A, Yıldız Ç, Seberi B, Gürakar M, Simsek C, Gürakar A. Usage of HCV viremic organs in liver transplantation to anti-HCV negative recipients: The current status and review of literature. Turk J Gastroenterol. 2019 Sep;30(9):771-775. doi: 10.5152/tjg.2019.18656. Review. PubMed PMID: 31530520.
25. Tasdogan BE, Akosman S, Gurakar M, Simsek C, Gurakar A. Update on Liver Transplantation: What is New Recently? Euroasian J Hepatogastroenterol. 2019 Jan-Jun;9(1):34-39. doi: 10.5005/jp- journals-10018-1293. PMID: 31988865; PMCID: PMC6969330.
26. Farha J, Fayad L, Kadhim A, Simsek C, Badurdeen DS, Ichkhanian Y, Itani MI, Kalloo AN, Khashab MA, Kumbhari V. Gastric Per-Oral Endoscopic Myotomy (G-POEM) for the Treatment of Gastric Stenosis Post-Laparoscopic Sleeve Gastrectomy (LSG). Obes Surg. 2019 Apr 19. doi: 10.1007/s11695- 019-03893-6. PubMed PMID: 31001761
27. Scarlotta M, Simsek C, Kim A. Liquid Biopsy in Solid Malignancy. Genetic Testing and Molecular Biomarkers. 2019 Apr;23(4):284-296. doi: 10.1089/gtmb.2018.0237. Epub 2019 Mar 27. PMID: 30916594.
28. Simsek C, Esin E, Yalcin S. Metronomic Chemotherapy: A Systematic Review of the Literature and Clinical Experience. J Oncol. 2019 Mar 20;2019:5483791. doi: 10.1155/2019/5483791. eCollection 2019. Review. PubMed PMID: 31015835; PubMed Central PMCID: PMC6446118.
29. Fayad L, Simsek C, Khashab MA, Kalloo AN, Kumbhari V. Gastrointestinal: Intragastric balloon: Gastric outlet obstruction or resting in the antrum? J Gastroenterol Hepatol. 2019 Jan;34(1):8. doi: 10.1111/jgh.14380. Epub 2018 Aug 6. PMID: 30084128.
30. Simsek C, Bostankolu B, Ozogul E, Saglam Ayhan A, Üner A, Büyükaşık Y. EBV-related Diffuse Large B-cell lymphoma in a Patient with Angioimmunoblastic T Cell Lymphoma: A Case Presentation. Turk J Haematol. 2018 Aug 1. doi: 10.4274/tjh.2018.0023. PubMed PMID: 30066674
31. Vahabov C, Simsek C, Purnak T. Pathogenesis of Nonalcoholic Fatty Liver Disease. Turkiye Klinikleri Gastroenterohepatology-Special Topics 12.2 (2019): 8-13.
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