
Name Surname:
Hande Canpınar
Title:
Assoc.Prof.
Department:
Basic Oncology
Contact:
She graduated from Hacettepe University Faculty of Science. Master’s and PhD degree from Hacettepe University Institute of Oncology, Tumor Biology and Immunology Department of Basic Oncology program was completed. The basic principles and applications of flow cytometry technology was educated in UK. His main research fields are cell mediated drug resistance and cell cycle analysis and immunophenotypicevaluation flow cytometric analysis of tumor cells.
1.Topaloğlu R, Saatçi Ü, Arıkan M, Canpınar H, Bakkaloğlu A, Kansu E. T-cell subsets interleukin-2 receptor expression and production of interleukin-2 in minimal change nephrotic syndrome. Pediatric Nephrology 1996, 8;6
2.Ündeğer Ü, Başaran N, Canpınar H, Kansu E. Immune alterations in lead exposed workers. Toxicology 1996, 109;167-172 3. Kostakoğlu L, Güç D, Canpınar H, Kars A, Alper E, Kıratlı P, Hayran M, Gündüz U, Kansu E. P-glycoprotein expression by technetium 99m MIBI scintigraphy in Hematologic malignancy. Jour Nuc Med. 1998, 39,1191-1197 4. Zengin N, Kars A, Özışık Y, Canpınar H, Türker A, Ruacan Ş. Aleukemicleukemia cutis in a patient with acute lymphoblastic leukemia. Jour Am Acad 1998, Dermatol,38,620-1 5. Eroglu A, Canpınar H, Kansu E. (1999) Influence of perioperative whole blood transfusions on lymphocyte subpopulations in patients with stage II breast cancer.Medical Oncology 1999, 16, 53-57 6. Yalçın B, Kutluk T, Kansu E, Göğüş S, Canpınar H, Akyuz C, Buyukpamukcu M. DNA content and proliferative activity in children with Neuroblastoma. Pediatric Hematology and Oncology 2000, 17:45-54 7. Aydin Z.D, Barista I, Canpınar H, Sungur A, Tekuzman G.Gastric Lymphomas in Turkey. Cancer 2000, 89:12-20 8. Guc D, Canpınar H, Kucukaksu C, Kansu E . Expression of complement regulatory proteins CR1, DAF, MCP and CD59 in haematological malignancies. Eur J Haematol 2000, 64:3-9 9. Kıratlı Ozgen P, Canpınar H, Ruacan Ş, Kansu E. Correlation of flow cytometric parameters and transferrin receptors with Gallium –67 scintigraphic images in lymphoma patients. Nuclear Medicine in Communication, 2000, 21, 925-931 10. Yariş N. Büyükpamukcu M, Kansu E, Canpınar H.Expression of adhesion molecules LFA-1, ICAM-1, CD44 and L-Selectin in childhood nonhodgkin lymphoma. Medical and Pediatric Oncology 2001, 30; 359-364 11. Akyuz C, Caglar K, Varan A, Kose V, Canpınar H, Kutluk T, Buyukpamukcu M. Myeloprotective effect of short term prechemotherapy recombinant granulocyte- macrophage colony stimulating factor. Medical and Pediatric Oncology, 2002, 38(1):67-9 12. Başaran N, Shubair M, Ündeğer Ü, Canpınar H, Kars A.Alterations in immune parameters in foundry and pottery workers. Toxicology 2002, 178;81-88 13. Karabudak R, Kurne A, Guc D, Sengelen M, Canpınar H, Kansu E. Effect of interferon b-1a on serum matrix metalloproteinase-9 (MMP-9) and tissue inhibitor ofmatrix metalloproteinase (TIMP-1) in relapsing remitting multiple sclerosis patients . J Neurol 2004, 251:279-283 14.Erman M, Abalı H, Oran B, Haznedaroğlu İ C, Canpınar H, Kirazlı Ş, Çelik İ. Tamoxifen- induced tissue factor pathway inhibitor reduction: a clue for an acquiredthrombophilic state? Annals of Oncology Annals of Oncology 2004, 15:1622- 1626 15. Dogan, A.L., Dogan, A., Canpınar, H., Düzgünçınar, O. , Demirpençe, E., (2004) “The effect of fludarabine on leukocyte functions, Chemotherapy 2004, 50(6):283-8 16.Koc Y, Oyan B, Kars A, Tekuzman G, Canpınar H, Kansu E. A randomized trial of continuous infusion versus bolus mitoxantrone in combination with cytarabine in newly diagnosed patients with acute myeloblastic leukemia. Hematological Oncology Hematological Oncology 2004, 22:43-53 17. Yalçın B, Canpınar H, Kutluk MT, Varan A, Akyüz C, Büyükpamukçu M.Cerebrospinal fluid soluble CD27 levels in children with non-Hodgkin Lymphomas. Pediatric Hematology and Oncology. 2004, 21:717-723, 2004 18. Yükrük F, Doğan AL, Canpınar H, Güç D, Akkaya EU.Water-soluble green perylenediimide (PDI) dyes as potential sensitiziers for photodynamic therapy. Organic letters 2005, 7;14, 2885-2887 19. Aksoy DY, Kerimoğlu U, Okur H, Canpınar H, Karaağaoğlu E, Yetkin S, Kansu E, Gedik O. ) Effects of prophylactic thyroid hormone replacement in euthyroid Hashimoto’s thyroiditis. Endocrine Journal 2005, 52:337-343 20. Aksu S, Beyazıt Y, Haznedaroglu I.C, Kekilli M, Canpınar H, Mısırlıoğlu M, Uner A, Tuncer S, Sayınalp N, Buyukasık Y, Goker H, Ozcebe O I. Enhanced expression of the local haematopoietic bone marrow renin-angiotensin system in polycythemia vera J Int Med Res 2005, 33(6):661-7 21. Aksu S, Beyazıt Y, Haznedaroğlu IC, Canpınar H, Kekilli M, Üner A, Sayınalp N, Büyükaşık Y, Göker H, Özcebe OI . Over-expression of angiotensin- converting enzyme (CD 143) on leukemic blasts as a clue for the activated local bone marrow RAS in AML Leukemia & Lymphoma 2006, 47(5):891-6 22. Canpınar H, Esendagli G., Kansu E., Gunel-Ozcan A., Guc D. Adhesion of Beta1 integrin to fibronectin regulates CAM-DR phenotype via p21WAF1/cip1 in HL60 acute myeloid leukemia (AML) cells.Turkish Journal of Medical Sciences 2008, 38(2):97-104. 23. Esendagli G, Canpınar H, Yilmaz G, Gunel-Ozcan A, Guc MO, Kansu E, Guc D. Primary tumor cells obtained from MNU-induced mammary carcinomas show immune heterogeneity which can be modulated by low-efficiency transfection of CD40L gene .Cancer Biol Ther. 2009, 27;8(2). 24. Esendagli G, Yilmaz G, Canpınar H, Gunel-Ozcan A, Guc M. O, Guc D. Co-existence of different tissue tumorigenesis in N-methyl-N-nitrosourea (MNU) induced mammary carcinoma model in Sprague-Dawley rats: A histopathological report. Laboratory Animals 2009, 43(1):60-4 25. Esendagli G, Gunel-Ozcan A, Canpınar H, Guc D. ) Molecular and functional analysis of a novel recombinant clone of rat (Rattus norvegicus) CD40 ligand (CD40L) gene. Molecular Biology Reports 2009, 36:83-89. 26. Esendağlı G, Canpınar H, Yılmaz G, Kaymaz F, Kansu E, Güç D. Fibronectin promotes the phorbol 12-myrıstate 13-acetate (PMA) induced macrophage differentiation in myeloid leukemia cells International Hematology;2009, 89(2):167-72. 27.Kılıç YA, Canpınar H, Güç D, Sayek İ. Otolog ve homolog kan transfüzyonunun karın içi enfeksiyon modelinde TNF-alfa düzeyleri ve sağkalıma etkisi. Turkish Journal of Trauma& Emergency Surgey 2009; 15(4):324-329 28. Esendagli G, Canpinar H, Dogan AL, Akkaya M, Kansu E, Guc D. Transfection of myeloid leukaemia cell lines is distinctively regulated by fibronectin substratum. Cytotechnology; 2009 ,61( 1-2) 45-53 29. Canpinar H,, Ozaltın F, Bakkaloglu A, Ozen S. Toll like receptor 2 and 4 cell surface expression reflectsendotoxin tolerance in Henoch-Schonlein Purpura Turkish Journal Of Pediatrics 2010 52:22-27 30. Aksoy Y, Kesikli K, Canpınar H. Does N-Acetyl Cysteine Protect Against Apoptosis in HL60 Cell Line? Turkish Journal of Biochemistry. Turkish Journal of Biochemistry–Turk J Biochem 2010; 35 (4) ; 333–339. 31. Kurne A, Guc D,Canpınar H, Aydın OF, Sayat G, Yörubulut M, Esendagli G, Karabudak R. Analysis of BAFF and TRAIL expression levels in multiple sclerosis patients: evaluation of expression under immunomodulatory therapy.Acta Neurol Scand (2011) 123(1):8-12. 32. Aksoy Y, Ercan A, Dalmizrak O, Canpinar H, Kartal Durmazlar SP,Bayazıt M. The Determination of Matrix Metalloproteinase 9 Activity and Gene Expression Levels in Behcet’s Disease Patients with Aneurysmal Complications. Clin Rheumatol. 2011 Apr;30(4):515-9. 33.Zeybek ND, Gulcelik NE, Kaymaz FF, Sarisozen C, Vural I, Bodur E, Canpinar H, Usman A, Asan E. Rosuvastatin induces apoptosis in cultured human papillary thyroid cancer cells. J Endocrinol. 2011 210, 105. 34. Aydın S,Canpınar H,Undeğer U,Güç D,Colakoğlu M,Kars A,Başaran N. Assessment of immunotoxicity and genotoxicity in workers exposed to low concentrations of formaldehyde Arch Toxicol.Arch Toxicol. 2013 Jan;87(1):145-53 35.Camurdanoglu, BZ, Esendağlı G,Ozdemir, E,Canpinar,H,Guc, D,Kansu, E. The effect of granulocyte colony stimulating factor receptor gene missense single nucleotide polymorphisms on peripheral blood stem cell enrichment. Cytokine, 2013 Feb;61(2):572-7. 36. Taspinar M, Ilgaz S, Ozdemir M, Ozkan T, Oztuna D, Canpinar H, Rey JA, Sunguroğlu A, Castresana JS, Ugur HC. Effect of lomeguatrib-temozolomide combination on MGMT promoter methylation and expression in primary glioblastoma tumor cells. Tumour Biol. 2013 34 (3):1935- 37. Halacli,Oskay S, Canpinar, H, Cimen, E, Sunguroğlu A.. .Effects of gamma irradiation on cell cycle, apoptosis and telomerase activity in p53 wild-type and deficient HCT116 colon cancer cell lines Oncology Letters 2013 6(3): 807-810 38.Ugur HC, Taşpınar M, Canpınar H, Rey JA, Castresana JS, Sungur A. Chemotherapeutic resistance in anaplastic astrocytoma cell lines treated with a temozolomide–lomeguatrib combination Molecular Biology Report 2014 Feb;41(2):697-703High School |
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: hcanpina@hacettepe.edu.tr